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Similarly, it has been calculated that with 3 × 10 5 FcεRI molecules per cell, which is close to the mean ± SEM of 1.7 ± 0.2 × 10 5 FcεRI molecules per LAD-2 human mast cell or RBL-2H3 cell measured in our work (Figure 1A), there would be a high probability of collisions 37