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Bacteria that produce high levels of ROS may have improved adhesion or the capacity to permeate mucous membranes, providing them with more proximal accessibility to cellular receptors (e.g., FPRs and TLRs)

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This is why, for example, short-acting benzodiazepines such as alprazolam and lorazepam are more difficult to discontinue than long-acting benzodiazepines such as diazepam and clonazepam