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For example, the compound glycyrrhizin derived from licorice ( Glycyrrhiza uralensis Fisch.) can significantly reduce the concentrations of pro-inflammatory cytokines IL-1β and TNF-α in inflammatory animal models and also decrease the levels of inflammatory mediators such as PGE2 and NO by inhibiting the activity of COX-2 and iNOS [88]

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How it works: Epitalon mimics a natural peptide produced by the pineal gland (called epithalamin) and is thought to work primarily by reactivating telomerase, the enzyme responsible for rebuilding telomeres