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Advanced analytical techniques are enabling researchers to track the compound's effects on global metabolite profiles, revealing complex interactions between NAD+ metabolism, methylation cycles, and other metabolic pathways that were previously unappreciated

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This functional disorder not only disrupts the normal regulatory mechanisms of blood vessels but also leads to increased blood pressure, arterial stiffness, and remodeling of small arteries, ultimately resulting in multi-organ damage (Boutouyrie et al., 2021